Enhancing SIV-specific immunity in vivo by PD-1 blockade
نویسندگان
چکیده
منابع مشابه
Enhancing SIV-Specific Immunity In Vivo by PD-1 Blockade
Chronic immunodeficiency virus infections are characterized by dysfunctional cellular and humoral antiviral immune responses. As such, immune modulatory therapies that enhance and/or restore the function of virus-specific immunity may protect from disease progression. Here we investigate the safety and immune restoration potential of blockade of the co-inhibitory receptor programmed death 1 (PD...
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ژورنال
عنوان ژورنال: Nature
سال: 2008
ISSN: 0028-0836,1476-4687
DOI: 10.1038/nature07662